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Antibiotics from a variety of classes seemed to be to seen to cause prolongation from the QT interval. Particularly fluoroquinolones (moxifloxacin, levofloxacin, etc.) and macrolides (erythromycin, azithromycin, etc.) ‘re normally associated with QT prolongation or induced torsade de pointes.10-13 Generally, high intravenous doses of erythromycin have been related to induced torsade de pointes.14 Erythromycin causes QT prolongation by blocking potassium channels and prolonging the action potential in the cardimyocytes.15 Fluroquinolones like sparfloxacin and moxifloxacin have been associated with major surge in QT prolongation.16 Newer fluoroquinolone antibiotics, including levofloxacin, do not have as great of the impact on the prolongation of the QT interval which may be due to the potency of the drug itself


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